| Monday |
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Opening session |
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| 8:30 AM |
Welcome |
Gabrielle Long |
Argonne National Lab, Advanced Photon Source |
| 8:45 AM |
Scope of workshop and vision for the Bio nanoprobe |
Gayle Woloschak |
Northwestern University, Dept. Radiology and Dept. Cell and Molecular Biology |
| 9:15 AM |
Hard x-ray microscopy: Capabilities and Opportunities |
Stefan Vogt |
Argonne National Lab, Advanced Photon Source |
| 9:45 AM |
Chemical imaging of biological tissues using a combination of synchrotron-based infrared and x-ray microspectroscopy and epifluorescence microscopy |
Lisa Miller |
Brookhaven National Lab, National Synchrotron Light Source |
| 10:15 AM |
coffee/tea break |
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| Session 1: |
Intrinsic Trace metals in Cell Biology and Pathology |
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| 10:45 AM |
Metalloproteomics in Angiogenesis |
David Glesne |
Argonne National Lab, Bio-Division |
| 11:15 AM |
Metal distributions in the hippocampus
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James Penner-Hahn
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University of Michigan, Department of Chemistry |
| 11:45 AM |
Signaling cardiac muscle injury with the Zn2+ chelator muscle-LIM protein |
Brad Palmer |
University of Vermont, Department of Molecular Physiology and Biophysics |
| 12:15 PM |
Manganese Versus Iron in Bacterial Survival |
Larry Wackett |
University of Minnesota, Department of Biochemistry |
| 12:45 PM |
lunch |
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| Session 2: |
Intrinsic trace metals and their role in development/inhibition of diseases |
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| 2:00 PM |
Trace Metals and Bacterial Infections |
Dirk Wagner |
University Freiburg, Medical Department |
| 2:30 PM |
Biomedical Applications of X-Ray microscopy |
Peter Lay |
University of Sydney,School of Chemistry |
| 3:00 PM |
Copper Exposure Enhances Alzheimer's Pathology |
Xudong Huang |
Massachusetts General Hospital, Institute for Neurodegenerative Disease |
| 3:30 PM |
coffee/tea break |
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| Session 3: |
Intrinsic trace metals and their role in development/inhibition of diseases (contd) |
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| 4:00 PM |
Metals in Malaria |
Tom O’Halloran
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Northwestern University, Dept. of Chemistry |
| 4:30 PM |
X-ray Fluorescence Spectroscopy In Situ Quantification of Metals/Elements in Alzheimer Disease |
Eileen Bigio |
Northwestern University, Dept. of Pathology |
| 5:00 PM |
The Fate of Platinum(IV) Anti-Cancer Agents in Cancer Cells and Spheroids |
Trevor Hambley |
University of Sydney,School of Chemistry |
| 5:30 PM |
conclude |
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| 6:00 PM |
no host dinner at guest house, (open discussion) |
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| Tuesday |
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| Session 4 |
Cell manipulation (intracellular and environmental) |
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| 8:30 AM |
Subcellular Localization of TiO2-DNA Nanocomposites |
Tanja Paunesku |
Northwestern University, Radiology Dept. |
| 9:00 AM |
Quantification of MR Contrast Agents in Mammalian Cells |
Thomas Meade |
Northwestern University, Dept. of Chemistry |
| 9:30 AM |
Cellular stoichiometry to global elemental cycles: the effect of Fe addition on cellular stoichiometry of oceanic protists |
Stephen Baines |
State University of New York, Marine Sciences Research Center |
| 10:00 AM |
coffee/tea break |
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| Discussion |
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| 10:30 AM |
Thrust of discussion |
Gayle Woloschak |
Northwestern University, Dept. Radiology and Dept. Cell and Molecular Biology |
| 10:40 AM |
Guided discussion |
Peter Ingram and Lee Makowskikowsky |
Duke University Medical Center and Argonne National Lab, Biosciences Division |
| 12:00 PM |
Summary and close-out (including to-do-list for participants |
Gayle Woloschak |
Northwestern University, Dept. Radiology and Dept. Cell and Molecular Biology |